Pro-Inflammatory Diet Is Correlated with High Veillonella rogosae, Gut Inflammation and Clinical Relapse of Inflammatory Bowel Disease

Inflammatory bowel diseases (IBD) are chronic conditions arising from an intricate interplay of genetics and environmental factors, associated with gut dysbiosis, inflammation, permeability. In this study, we investigated whether the inflammatory potential diet is microbiota profile, permeability in forty patients IBD clinical remission. The dietary index (DII) score was used to assess diet. fecal profile analyzed using 16SrRNA (V3–V4) gene sequencing, while zonulin calprotectin levels were measured enzyme-linked immunosorbent assays. We found a positive correlation between DII elevated (Rho = 0.498; p 0.001), but not levels. Although α- β-diversity did significantly differ across quartiles, most pro-inflammatory group exhibited higher abundance Veillonella rogosae (p 0.026). addition, some specific bacteria sequences showed exponential behavior quartiles or ≤ 0.050). This included sq702. 0.419, 0.007). DII, calprotectin, identified as significant predictors 6-month disease relapse Our findings suggest relationship intake remission, which may contribute relapse.